ASTM E1163 - 10(2019) - Standard Test Method for Estimating Acute Oral Toxicity in Rats

ASTM E1163 - 10(2019)

Standard Test Method for Estimating Acute Oral Toxicity in Rats

Status : Current   Published : February 2019

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HARDCOPY



1.1 This test method determines the lethality (LD50 value, slope and 95 % confidence interval (CI)) and signs of acute toxicity from a material using a limited number of rats. The technique used in this test method is referred to as the “Stagewise, Adaptive Dose Method.” 2 This test method is an alternative to the classical LD50 test and is applicable to both liquids and solids.

1.2 This test method is not recommended for test materials which typically produce deaths beyond two days postdosing.

1.3  This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.

1.4  This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.




Standard NumberASTM E1163 - 10(2019)
TitleStandard Test Method for Estimating Acute Oral Toxicity in Rats
StatusCurrent
Publication Date01 February 2019
Normative References(Required to achieve compliance to this standard)No other standards are normatively referenced
Informative References(Provided for Information)No other standards are informatively referenced
Descriptors chemicals, LD50, oral toxicity, pesticides, rats
ICS65.100.99
PublisherASTM
FormatA4
DeliveryYes
Pages3
File Size63 KB
Price£36.00


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