ASTM E1619 - 11(2016) - Standard Test Method for Chronic Oral Toxicity Study in Rats

ASTM E1619 - 11(2016)

Standard Test Method for Chronic Oral Toxicity Study in Rats

Status : Current   Published : February 2016



1.1 This test method covers a long-term study to determine the effects of a substance in a mammalian species such as the rat following prolonged and repeated oral exposure. Under the conditions of the chronic toxicity test, effects that require a long latency period or that are cumulative should become manifest.

1.2 This test method assumes that the user is knowledgeable in mammalian toxicology and related pertinent areas, and relies heavily on the judgment of the evaluator.

1.3 The values stated in SI units are to be regarded as the standard. The inch-pound units given in parentheses are for information only.

1.4  This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. For specific hazard statements, see Section 6.

Standard NumberASTM E1619 - 11(2016)
TitleStandard Test Method for Chronic Oral Toxicity Study in Rats
Publication Date01 February 2016
Normative References(Required to achieve compliance to this standard)No other standards are normatively referenced
Informative References(Provided for Information)No other standards are informatively referenced
Descriptors Blood chemistry, Chronic toxicity, Feed efficiency, Gavage, Hematology, LDinf50/inf, Necropsy, Oral, Pesticide, Rat, Toxicity, Urinalysis
File Size74 KB

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