BS ISO 16000-39:2019 - Indoor air. Determination of amines. Analysis of amines by (ultra-) high-performance liquid chromatography coupled to high resolution or tandem mass spectrometry

BS ISO 16000-39:2019

Indoor air. Determination of amines. Analysis of amines by (ultra-) high-performance liquid chromatography coupled to high resolution or tandem mass spectrometry

Status : Current   Published : June 2019

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This document, along with ISO 16000-38, specifies the measurement method for determining the mass concentration of primary, secondary and tertiary aliphatic and aromatic amines in indoor air using accumulated sampling and high-performance liquid chromatography (HPLC) coupled with tandem mass spectrometry (MS-MS) or high-resolution mass spectrometry (HRMS). The analytical procedure is covered by this document. The sampling procedure and the manufacturing of the samplers are covered by ISO 16000-38.

This document describes specifications for the chromatography and the mass spectroscopy for the amines. Measurement results are expressed in µg/m3.

Although primarily intended for the measurement of amines listed in Tables A.1 and A.2, it can also be used for the measurement of other amines in indoor air. This document gives instructions and describes procedures for the inclusion of other amines.

The range of application of this document concerning the concentrations of amines in indoor air depends on the linear range of the calibration line and hence on the gas sample volume (here: from 5 l up to 100 l), the eluate volume (from 1 ml up to 5 ml), the injection volume (from 1 µl up to 10 µl) and the sensitivity of the analytical equipment (e.g. linear range from 2 pg up to 2 ng amine). The range of application can be expected to be from approximately 0,002 µg/m3 (100 l sample) up to 2 000 µg/m3 (5 l sample) for a common analytical equipment (e.g. Waters „TQD“) for the majority of the amines listed in Tables A.1 and A.2. The analysis of derivatives of ethanolamine is usually about 10 times more sensitive and the analysis of short-chained aliphatic amines is usually about 10 times less sensitive than the analysis of an average amine.

The performance data of the analytical method is given in Annex B, particularly in Tables B.1 and B.2.

This document can be used also for the determination of amines in water if the detection limit is sufficient.

This document does not cover the determination of isocyanates in indoor air (nor in water samples) as corresponding amines (covered by ISO 17734-1 and ISO 17734-2).




Standard NumberBS ISO 16000-39:2019
TitleIndoor air. Determination of amines. Analysis of amines by (ultra-) high-performance liquid chromatography coupled to high resolution or tandem mass spectrometry
StatusCurrent
Publication Date06 June 2019
Normative References(Required to achieve compliance to this standard)ISO 16000-38
Informative References(Provided for Information)ISO 9702:1996, ISO 17734, ISO 12219-1, ISO/IEC 17025:2017, ISO 12219-4, ISO 16000-28, VDI 2467-2:1991
International RelationshipsISO 16000-39:2019
Draft Superseded By18/30321730 DC
DescriptorsHigh performance liquid chromatography, Amines (aliphatic), Mass spectrometry, Air, Analysis
ICS13.040.20
CommitteeEH/2/5
ISBN978 0 580 89882 2
PublisherBSI
FormatA4
DeliveryYes
Pages22
File Size836 KB
Price£130.00


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