BS EN 16418:2014 - Paper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)

BS EN 16418:2014

Paper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)

Status : Confirmed, Current   Published : April 2014

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HARDCOPY



This European Standard specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board intended to come into contact with foodstuffs using specifically the HepG2 cell line. Compared to the EN 15845[1], HepG2 cells are more representative of a human oral exposure to xenobiotics, due to the presence in the cells of phase I, II and III enzymes of the metabolism.




Standard NumberBS EN 16418:2014
TitlePaper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)
StatusConfirmed, Current
Publication Date30 April 2014
Confirm Date16 March 2020
Normative References(Required to achieve compliance to this standard)EN 645, EN 647
Informative References(Provided for Information)ISO 3696:1987, EN 15845, EN ISO 3696
International RelationshipsEN 16418:2014
Draft Superseded By12/30259424 DC
DescriptorsBoard (paper), Paper products, Aqueous extraction methods, Paper, Specimen preparation, Materials in contact with food, Chemical analysis and testing
ICS85.060
Title in FrenchPapier et carton. Détermination de l'effet cytotoxique d'extraits aqueux en utilisant une lignée cellulaire d'hépatome possédant des enzymes du métabolisme (cellules HepG2)
Title in GermanPapier und Pappe. Bestimmung der Zytotoxizität von wässrigen Extrakten unter Verwendung einer metabolisch kompetenten Hepatom-Zelllinie (HepG2)
CommitteePAI/11
ISBN978 0 580 78119 3
PublisherBSI
FormatA4
DeliveryYes
Pages24
File Size1.045 MB
Price£182.00


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